Listar por tema "Enfermedad de Alzheimer"

Mostrando ítems 21-28 de 28

    • Neurovascular dysfunction and vascular amyloid accumulation as early events in Alzheimer's disease 

      Apatiga Pérez, Ricardo; Soto Rojas, Luis O.; Campa Córdoba, B. Berenice; Luna Viramontes, Nabil Itzi; Cuevas, Elvis; Villanueva‑Fierro, Ignacio; Ontiveros Torres, Miguel Angel; Bravo Múñoz, Marely; Flores Rodríguez, Paola; Garces Ramírez, Linda; Cruz, Fidel de la; Montiel Sosa, José Francisco; Pacheco Herrero, Mar; Luna Muñoz, José (Metabolic Brain Disease, 2021-07)
      Alzheimer's disease (AD) is clinically characterized by a progressive loss of cognitive functions and short-term memory. AD patients present two distinctive neuropathological lesions: neuritic plaques and neurofibrillary ...

    • The neurovascular unit dysfunction in Alzheimer’s disease 

      Soto-Rojas, Luis O.; Pacheco-Herrero, Mar; Martínez-Gómez, Paola A.; Campa-Córdoba, B. Berenice; Apátiga-Pérez, Ricardo; Villegas-Rojas, Marcos M.; Harrington, Charles R.; Cruz, Fidel de la; Garcés-Ramírez, Linda; Luna-Muñoz, José (International Journal o f Molecular Sciences, 2021-02-16)
      Alzheimer’s disease (AD) is the most common neurodegenerative disease worldwide. Histopathologically, AD presents with two hallmarks: neurofibrillary tangles (NFTs), and aggregates of amyloid peptide (A ) both in the ...

    • Packages of care for dementia in low- and middle-income countries. 

      Prince, Martin J.; Acosta, Daisy; Castro-Costa, E.; Jackson, J.; Shaji, K. S. (PolS Medicine, 2009)
      This is the fifth in a series of articles highlighting the delivery of "packages of care" for mental health disorders in low- and middle-income countries. Packages of care are combinations of treatments aimed at improving ...

    • Population normative data for the 10/66 Dementia Research Group cognitive test battery from Latin America, India and China: a cross-sectional survey. 

      Sosa, Ana Luisa; Albanese, Emiliano; Prince, Martin J.; Acosta, Daisy; Ferri, Cleusa P.; Huang, Yueqin; Jacob, K. S.; Llibre Rodríguez, Juan J.; Salas, Aquiles; Yang, Fang; Gaona, Ciro; Jotheeswaran, A. T.; Rodríguez Pichardo, Guillermina; Rojas de la Torre, Gabriela; Williams, Joseph D.; Stewart, Robert (BMC Neurology, 2009)
      1) To report site-specific normative values by age, sex and educational level for four components of the 10/66 Dementia Research Group cognitive test battery; 2) to estimate the main and interactive effects of age, sex, ...

    • Prediction of dementia risk in low-income and middleincome countries (the 10/66 Study): an independent external validation of existing models 

      Stephan, Blossom C M; Pakpahan, Eduwin; Siervo, Mario; Licher, Silvan; Muniz-Terrera, Graciela; Mohan, Devi; Acosta, Daisy; Rodriguez Pichardo, Guillermina; Sosa, Ana Luisa; Acosta, Isaac; Llibre-Rodriguez, Juan J; Prince, Martin; Robinson, Louise; Prina, Matthew (Elsevier Ltd., 2020-04)
      To date, dementia prediction models have been exclusively developed and tested in high-income countries (HICs). However, most people with dementia live in low-income and middle-income countries (LMICs), where dementia risk ...

    • Programa psicoeducativo para familias con integrante con alzheimer en el Instituto del Abuelo. Santo domingo, marzo-julio 2013. 

      Caminero Castillo, Paola Yadirha; Zapata Padilla, Racel Zoraina (Universidad Nacional Pedro Henriquez Ureña, 2013-08)
      Se aplicaron escalas (nivel de sobrecarga del cuidador de Zarit y escala de Ansiedad de Hamilton) y un cuestionario (Cuestionario del perfil del cuidador) a 20 cuidadores de ambos sexos que actualmente llevan a sus ...

    • Progranulin mutations in clinical and neuropathological Alzheimer’s disease 

      Vardarajan, Badri N.; Reyes-Dumeyer, Dolly; L. Piriz1, Angel; Lantigua, Rafael A.; Medrano, Martin; Rivera, Diones; Jiménez-Velázquez, Ivonne Z.; Martin, Eden; Pericak-Vance, Margaret A.; Bush, William; Farrer, Lindsay; Haines, Jonathan L.; Wang, Li-San; Yee Leung, Yuk; Schellenberg, Gerard; Kukull, Walter; De Jager, Philip; Bennett, David A.; Schneider, Julie A.; Alzheimer’s Disease Sequencing Project; Mayeux, Richard (Alzheimers Dement., 2022-12-10)
      Progranulin (GRN) mutations occur in frontotemporal lobar degeneration (FTLD) and in Alzheimer’s disease (AD), often with TDP-43 pathology. We determined the frequency of rs5848 and rare, pathogenic GRN mutations in two ...

    • Rare genetic variation in fibronectin 1 (FN1) protects against APOEε4 in Alzheimer’s disease 

      Bhattarai, Prabesh; Iniyan Gunasekaran, Tamil; Belloy, Michael E.; Reyes-Dumeyer, Dolly; Jülich, Dörthe; Tayran, Hüseyin; Yilmaz, Elanur; Flaherty, Delaney; Turgutalp, Bengisu; Sukumar, Gauthaman; Alba, Camille; Martínez McGrath, Elisa; Hupalo, Daniel N.; Bacikova, Dagmar; Le Guen, Yann; Lantigua, Rafael; Medrano, Martin; Rivera, Diones; Recio, Patricia; Nuriel, Tal; Ertekin-Taner, Nilüfer; Teich, Andrew F.; Dickson, Dennis W.; Holley, Scott; Greicius, Michael; Dalgard, Clifton L.; Zody, Michael; Mayeux, Richard; Kizil, Caghan; Vardarajan, Badri N. (Acta Neuropathologica, 2024-03)
      The risk of developing Alzheimer’s disease (AD) significantly increases in individuals carrying the APOEε4 allele. Elderly cognitively healthy individuals with APOEε4 also exist, suggesting the presence of cellular ...