Listar por autor "Blanco-Alvarez, Víctor Manuel"

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    • Mechanistic Insight from Preclinical Models of Parkinson’s Disease Could Help Redirect Clinical Trial Efforts in GDNF Therapy 

      Delgado-Minjares, Karen M.; Martinez-Fong, Daniel; Martínez-Dávila, Irma A.; Bañuelos, Cecilia; Gutierrez-Castillo, M. E.; Blanco-Alvarez, Víctor Manuel; Cardenas-Aguayo, Maria-del-Carmen; Luna-Muñoz, José; Pacheco-Herrero, Mar; Soto-Rojas, Luis O. (Int. J. Mol. Sci, 2021)
      Parkinson’s disease (PD) is characterized by four pathognomonic hallmarks: (1) motor and non-motor deficits; (2) neuroinflammation and oxidative stress; (3) pathological aggregates of the α-synuclein (α-syn) protein; (4) ...

    • Oxidative stress and mitochondrial complex I dysfunction correlate with neurodegeneration in an -synucleinopathy animal model 

      Morales-Martínez, Adriana; Martínez-Gómez, Paola A.; Martinez-Fong, Daniel; Villegas-Rojas, Marcos M.; Pérez-Severiano, Francisca; Del Toro-Colín, Miguel A.; Delgado-Minjares, Karen M.; Blanco-Alvarez, Víctor Manuel; Leon-Chavez, Bertha Alicia; Aparicio-Trejo, Omar Emiliano; Baéz-Cortés, Mauricio T.; Cardenas-Aguayo, Maria-del-Carmen; Luna-Muñoz, José; Pacheco-Herrero, Mar; Angeles-López, Quetzalli D.; Martínez-Dávila, Irma A.; Salinas-Lara, Citlaltepetl; Romero-López, José Pablo; Sánchez-Garibay, Carlos; Méndez-Cruz, Adolfo R.; Soto-Rojas, Luis O. (International Journal o f Molecular Sciences Article, 2022-09-27)
      The α-synucleinopathies constitute a subset of neurodegenerative disorders, of which Parkinson's disease (PD) is the most common worldwide, characterized by the accumulation of misfolded α-synuclein in the cytoplasm of ...