Latin American anaphylaxis registry
Fecha
2023-01-23Autor
Jares, Edgardo J.
Cardona, Victoria
Gómez, Maximiliano
Bernstein, Jonathan A.
Rosario Filho, Nelson A.
Cherrez-Ojeda, Ivan
Ensina, Luis Felipe
De Falco, Alicia
Díaz, María C.
Chávez Vereau, Pierre A.
Rocha Felix, Mara M.
Lavrut, Jorge
Moreno Laflor, Oscar I.
Latour Staffeld, Patricia
Piraino, Pedro
Alacaraz Duarte, Perla
Ivancevich, Juan C.
Dabove, Fabian
Giavina-Bianchi, Pedro
Tinoco Moran, Iván O.
Nunes Oliviera, Fabiana A.
Monsell, Silvana
Souza, María V.
Cepeda, Alfonso M.
Slullitel, Pablo D.
Morfin-Maciel, Blanca M.
Metadatos
Mostrar el registro completo del ítemResumen
Recent data about clinical features, triggers and management of anaphylaxis in
Latin America is lacking. To provide updated and extended data on anaphylaxis in this region.
An online questionnaire was used, with 67 allergy units involved from 12 Latin-American
countries and Spain. Among data recorded, demographic information, clinical features, severity,
triggering agents, and treatment were received. Eight hundred and seventeen anaphylactic reactions were recorded. No difference in severity, regardless of pre-existing allergy or asthma history was found. Drug induced anaphylaxis (DIA) was most frequent (40.6%), followed by food induced anaphylaxis (FIA) (32.9%) and venom induced anaphylaxis (VIA) (12%). FIA and VIA were more common in children-adolescents. Nonsteroidal anti-inflammatory drugs (NSAIDs) and beta-lactam antibiotics (BLA) were the most frequent drugs involved. Milk (61.1% of FIA) and egg (15.4% of FIA) in children, and shellfish
(25.5% of FIA), fresh fruits (14.2% of FIA), and fish (11.3% of FIA) in adults were the most common
FIA triggers. Fire ants were the most frequent insect triggers, and they induced more severe reactions
than triggers of FIA and DIA (p < 0.0001). Epinephrine was used in 43.8% of anaphylaxis
episodes. After Emergency Department treatment, epinephrine was prescribed to 13% of patients.
Conclusions: Drugs (NSAIDs and BLA), foods (milk and egg in children and shellfish, fruits and
fish in adults) and fire ants were the most common inducers of anaphylaxis. Epinephrine was used
in less than half of the episodes emphasizing the urgent need to improve dissemination and
implementation of anaphylaxis guidelines.
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