Buscar
Mostrando ítems 1-5 de 5
Oxidative stress and mitochondrial complex I dysfunction correlate with neurodegeneration in an -synucleinopathy animal model
(International Journal o f Molecular Sciences Article, 2022-09-27)
The α-synucleinopathies constitute a subset of neurodegenerative disorders, of which Parkinson's disease (PD) is the most common worldwide, characterized by the accumulation of misfolded α-synuclein in the cytoplasm of ...
Prevalence of parkinsonism and Parkinson disease in urban and rural populations from Latin America: A community based study
(The Lancet Regional Health - Americas 2022;7: 100136, 2021-12-10)
Age and gender specific prevalence rates for parkinsonism and Parkinson’s disease (PD) are important
to guide research, clinical practice, and public health planning; however, prevalence estimates in Latin America
(LatAm) ...
Burden of Parkinsonism and Parkinson's disease on health service use and outcomes in Latin America
(Journal of Parkinson's Disease, 2023-11-03)
Little is known about the burden of parkinsonism and Parkinson’s disease (PD) in Latin America. Better understanding of health service use and clinical outcomes in PD is needed to improve its prognosis.
The aim of the ...
Mechanistic Insight from Preclinical Models of Parkinson’s Disease Could Help Redirect Clinical Trial Efforts in GDNF Therapy
(Int. J. Mol. Sci, 2021)
Parkinson’s disease (PD) is characterized by four pathognomonic hallmarks: (1) motor
and non-motor deficits; (2) neuroinflammation and oxidative stress; (3) pathological aggregates of
the α-synuclein (α-syn) protein; (4) ...
Prevalence and impact of neuropsychiatric symptoms in normal aging and neurodegenerative syndromes: A population-based study fromLatin America
(Alzheimer’s Dement, 2023-06-23)
Neuropsychiatric symptoms (NPSs) are common in neurodegenerative diseases; however, little is known about the prevalence of NPSs in Hispanic populations. Neuropsychiatric symptoms (NPSs) are common in neurodegenerative ...