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The association between, depression, anxiety, and mortality in older people across eight low‐ and middle‐income countries: Results from the 10/66 cohort study
(wileyonlinelibrary.com/journal/gps, 2019-09-15)
Objectives: Depression and anxiety are common mental disorders in later life. Few
population‐based studies have investigated their potential impacts on mortality in
low‐ and middle‐income countries (LMICs). The aim of ...
Prediction of dementia risk in low-income and middleincome countries (the 10/66 Study): an independent external validation of existing models
(Elsevier Ltd, 2020-04)
To date, dementia prediction models have been exclusively developed and tested in high-income countries
(HICs). However, most people with dementia live in low-income and middle-income countries (LMICs), where
dementia ...
Mortality Rates and Mortality Risk Factors in Older Adults with Dementia from Low- and Middle-Income Countries: The 10/66 Dementia Research Group Population-Based Cohort Study
(Journal of Alzheimer’s Disease 75 (2020) 581–593, 2020-03-09)
Background: Dementia is the main cause of disability in older people living in low- and middle-income countries (LMIC).
Monitoring mortality rates and mortality risk factors in people with dementia (PwD) may contribute ...
Leg length, skull circumference, and the incidence of dementia in Latin America and China: a 10/66 population-based cohort study
(PLOS ONE, 2018-04-18)
Adult leg length is influenced by nutrition in the first few years of life. Adult head circumference
is an indicator of brain growth. Cross-sectional studies indicate inverse associations
with dementia risk, but there ...
Neighbourhood environment and dementia in older people from high-, middle- and low-income countries: results from two population-based cohort
(BMC Public Health, 2020)
A growing number of studies have explored how features of the neighbourhood environment can
be related to cognitive health in later life. Yet few have focused on low- and middle-income countries and
compared the results ...
Biomarkers for dementia in Latin American countries: Gaps and opportunities
(Alzheimer’s & Dementia, 2022-01-15)
Limited knowledge on dementia biomarkers in Latin American and Caribbean (LAC)
countries remains a serious barrier. Here, we reported a survey to explore the ongoing
work, needs, interests, potential barriers, and ...
Biomarker Candidates for Alzheimer’s Disease Unraveled through In Silico Differential Gene Expression Analysis
(Basel, 2022-05-07)
Alzheimer’s disease (AD) is neurodegeneration that accounts for 60–70% of dementia cases.
Symptoms begin with mild memory difficulties and evolve towards cognitive impairment. The
underlying risk factors remain primarily ...
A Novel Automatic Quantification Protocol for Biomarkers of Tauopathies in the Hippocampus and Entorhinal Cortex of Post-Mortem Samples Using an Extended Semi-Siamese U-Net
(Biology., 2022-07-28)
Efforts have been made to diagnose and predict the course of different neurodegenerative
diseases through various imaging techniques. Particularly tauopathies, where the tau polypeptide
is a key participant in molecular ...
The protocols for the 10/66 dementia research group population-based research programme
(BMC Public Health, 2007-07-07)
Latin America, China and India are experiencing unprecedentedly rapid demographic ageing with an
increasing number of people with dementia. The 10/66 Dementia Research Group's title refers to the 66% of people with dementia ...
Current status and challenges of stem cell treatment for Alzheimer’s disease
(Journal of Alzheimer’s Disease, 2021)
Neurodegenerative diseases called tauopathies, such as Alzheimer’s disease (AD), frontotemporal dementia, progressive supranuclear palsy, and Parkinson’s disease, among others, are characterized by the pathological processing ...