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Mostrando ítems 157-176 de 265
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Male pseudohermaphroditism due to multiple defects in steroid-biosynthetic microsomal mixed-function oxidases — a new variant of congenital adrenal hyperplasia
(New England Journal of Medicine, 1985-11-07)A six-month-old 46,XY infant with a female phenotype and ambiguous genitalia was evaluated for male pseudohermaphroditism. The principal findings were (1) low basal plasma levels of all measured C19 steroids and their ... -
Male pseudohermaphroditism secondary to 5α-reductase deficiency—A model for the role of androgens in both the development of the male phenotype and the evolution of a male gender identity
(Journal of Steroid Biochemistry, 1979)Male pseudohermaphroditism secondary to 5α-reductase deficiency is reviewed. At birth, the affected males (46 XY) have a clitoral-like phallus, bifid scrotum and urogenital sinus with the testes in the inguinal canals or ... -
Measuring disability across cultures the psychometric properties of the WHODAS II in older people from seven low- And middle-income countries. the 10/66 Dementia research group population-based survey
(International Journal of Methods in Psychiatric Research, 2010)We evaluated the psychometric properties of the 12-item intervieweradministered screener version of the World Health Organization Disability Assessment Schedule – version II (WHODAS II) among older people living in seven ... -
Mechanistic Insight from Preclinical Models of Parkinson’s Disease Could Help Redirect Clinical Trial Efforts in GDNF Therapy
(Int. J. Mol. Sci, 2021)Parkinson’s disease (PD) is characterized by four pathognomonic hallmarks: (1) motor and non-motor deficits; (2) neuroinflammation and oxidative stress; (3) pathological aggregates of the α-synuclein (α-syn) protein; (4) ... -
Medical students’ perceptions about the added educational value of student-run HIV/AIDS educational campaigns in the Dominican Republic
(Global Health Research and Policy, 2016-12)This purpose of this report was to examine the perceptions of medical students about the strengths, limitations, and recommendations for improvement of the first known student-run HIV/AIDS educational campaigns in the ... -
Medicinal plants in the Dominican Republic and their possible role in public health care
(International Society for Horticultural Science, 2016)In the Dominican Republic, one can distinguish two medical systems: the formal medical system and the informal medical system. The formal medical system is based on the western conventional medical system. The informal ... -
Mineralogical analysis with the firing temperature of limestone and clay mixture from Dominican Republic using Mössbauer spectroscopy and X-ray powder diffractometry
(Springer Link, 1991)The study of a limestone and clay mixture using Mössbauer spectroscopy, and X-ray powder spectrometry (XRD) for different firing temperatures are presented. This type of mixture is used in raw minerals in order to obtain ... -
Moisture condition evaluation in a sixteenth century building using non-destructive techniques
(Springer, Cham, 2022-11-01)The objective of this study is to analyze the surface moisture conditions in a sixteenth century building located in the colonial city of Santo Domingo, Dominican Republic, by non-destructive methods. Two techniques were ... -
Molecular Processing of Tau Protein in Progressive Supranuclear Palsy: Neuronal and Glial Degeneration
(IOS Press BV, 2021)Alzheimer's disease (AD) and progressive supranuclear palsy (PSP) are examples of neurodegenerative diseases, characterized by abnormal tau inclusions, that are called tauopathies. AD is characterized by highly insoluble ... -
Monitoring temporal changes in SARS-CoV-2 spike antibody levels and variant-specific risk for infection, Dominican Republic, March 2021–August 2022
(RESEARCH, 2023)To assess changes in SARS-CoV-2 spike binding antibody prevalence in the Dominican Republic and implications for immunologic protection against variants of concern, we prospectively enrolled 2,300 patients with undif ... -
Morphological and fractal properties of brain tumors
(Frontiers in Physiology, 2022-06-27)Tumor interface dynamics is a complex process determined by cell proliferation and invasion to neighboring tissues. Parameters extracted from the tumor interface fluctuations allow for the characterization of the particular ... -
Mortality Rates and Mortality Risk Factors in Older Adults with Dementia from Low- and Middle-Income Countries: The 10/66 Dementia Research Group Population-Based Cohort Study
(Journal of Alzheimer’s Disease 75 (2020) 581–593, 2020-03-09)Background: Dementia is the main cause of disability in older people living in low- and middle-income countries (LMIC). Monitoring mortality rates and mortality risk factors in people with dementia (PwD) may contribute ... -
Mössbauer and X-ray fluorescence study of sediments from Samana Bay, Dominican Republic
(Journal of Radioanalytical and Nuclear Chemistry, 1995-08)The chemical state of iron in sediments collected from Samana Bay has been determined by Mössbauer spectroscopy. The Mössbauer spectra were composed of two paramagnetic doulets, which correspond to high=spin ferric and ... -
Mössbauer study on indigenous ceramics in La Isabela City, Dominican Republic
(Springer Link, 1990)The following study deals with the determination of the firing temperature of some of the ceramics found in La Isabela City, Dominican Republic, first settlement of the Spaniards in the New World. These ceramics were ... -
Multifractal analysis of brain tumor interface in glioblastoma
(PulbMed, 2024)The dynamics of tumor growth is a very complex process, generally accompanied by numerous chromosomal aberrations that determine its genetic and dynamical heterogeneity. Consequently, the tumor interface exhibits a non-regular ... -
Multiple unhealthy behaviors share equivalent profiles of readiness for change in patients with type 2 Diabetes
(International Journal of Environmental Research and Public Health, 2021-03-31)Few studies have considered more than one behavior, despite the tendency towards multiple behaviors, and there are none that have focused on a Latino population. We determined the concurrence of four unhealthy behaviors ... -
Mutations in CYP11B1 gene: phenotype-genotype correlations
(Am J Med Genet A ., 2003-10)11beta-hydroxylase deficiency, an autosomal recessive disorder, is the second most common cause of congenital adrenal hyperplasia. We studied four subjects with classic 11beta-hydroxylase deficiency and severe hypertension: ... -
The Nairobi Declaration—Reducing the burden of dementia in low- and middle-income countries (LMICs): Declaration of the 2022 Symposium on Dementia and Brain Aging in LMICs
(Alzheimer's Association, 2023-03-11)Delegates of the 2022 Symposium on Dementia and Brain Aging in Low- and Middle-Income Countries, representing over 40 countries, met in Nairobi, Kenya, December 5–9 to highlight advances in dementia prevention, diagnosis, ... -
Natural disasters
(2019)Natural disasters can cause a rupture of the daily routine with an essential impact on the local resources and the standard functionality of the population. It is critical that as health care personnel, we are familiar ... -
Neighbourhood environment and dementia in older people from high-, middle- and low-income countries: results from two population-based cohort
(BMC Public Health, 2020)A growing number of studies have explored how features of the neighbourhood environment can be related to cognitive health in later life. Yet few have focused on low- and middle-income countries and compared the results ...
