• Human Dental Pulp Stem Cells Display a Potential for Modeling Alzheimer Disease-Related Tau Modifications 

      Karlen, Gazarian; Ramírez García, Luis; Tapía Orozco, Luis; Luna Muñoz, José; Pacheco Herrero, Mar (Frontiers Media S. A., 2021)
      We present here the first description of tau in human dental pulp stem cells (DPSCs) evidenced by RT-PCR data on expression of the gene MAPT and by immunocytochemical detection of epitopes by 12 anti-tau antibodies. The ...
    • Molecular Processing of Tau Protein in Progressive Supranuclear Palsy: Neuronal and Glial Degeneration 

      Martínez-Maldonado, Alejandra; Ontiveros-Torres, Miguel Ángel; Harrington, Charles R.; Montiel-Sosa, José Francisco; Prandiz, Raúl García Tapia; Bocanegra-López, Patricia; Sorsby-Vargas, Andrew Michael; Bravo-Muñoz, Marely; Florán-Garduño, Benjamín; Villanueva-Fierro, Ignacio; Perry, George; Garcés-Ramírez, Linda; de la Cruz, Fidel; Martínez-Robles, Sandra; Pacheco-Herrero, Mar; Luna-Muñoz, José (IOS Press BV, 2021)
      Alzheimer's disease (AD) and progressive supranuclear palsy (PSP) are examples of neurodegenerative diseases, characterized by abnormal tau inclusions, that are called tauopathies. AD is characterized by highly insoluble ...