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Mostrando ítems 191-200 de 221
Drug-induced liver injury: A management position paper from the Latin American Association for Study of the liver
(Annals of Hepatology, 2021)
Idiosyncratic drug-induced liver injury (DILI) caused by xenobiotics (drugs, herbals and dietary supplements)
is an uncommon cause of liver disease presenting with a wide range of phenotypes and
disease severity, acute ...
Identification of Rgp1p, a novel Golgi recycling factor, as a protein required for efficient localization of yeast casein kinase 1 to the plasma membrane
(Journal of Cell Science, 2000)
The Yck1p and Yck2p casein kinase 1 isoforms in yeast are essential peripheral plasma membrane-associated protein kinases with roles in endocytosis, cellular morphogenesis and cytokinesis. The membrane targeting of these ...
Burden of Parkinsonism and Parkinson's disease on health service use and outcomes in Latin America
(Journal of Parkinson's Disease, 2023-11-03)
Little is known about the burden of parkinsonism and Parkinson’s disease (PD) in Latin America. Better understanding of health service use and clinical outcomes in PD is needed to improve its prognosis.
The aim of the ...
Mechanistic Insight from Preclinical Models of Parkinson’s Disease Could Help Redirect Clinical Trial Efforts in GDNF Therapy
(Int. J. Mol. Sci, 2021)
Parkinson’s disease (PD) is characterized by four pathognomonic hallmarks: (1) motor
and non-motor deficits; (2) neuroinflammation and oxidative stress; (3) pathological aggregates of
the α-synuclein (α-syn) protein; (4) ...
What trauma patients need: the European dilemma
(European Journal of Trauma and Emergency Surgery, 2022)
There is a need for implementation and maturation of an inclusive trauma system in every country in Europe, with patient centered care by dedicated surgeons. This process should be initiated by physicians and medical ...
Trauma quality improvement program: a retrospective analysis from a middle eastern National Trauma Center
(Healthcare, 2023-10-31)
The Trauma Quality Improvement Program (American College of Surgery
(ACS-TQIP)) uses the existing infrastructure of the Committee on Trauma programs and provides
feedback to participating hospitals on risk-adjusted ...
Physical and Chemical Characterisation of the Pigments of a 17th-Century Mural Painting in the Spanish Caribbean
(MDPI, 2021)
The arrival of Spaniards in the Caribbean islands introduced to the region the practice of
applying pigments onto buildings. The pigments that remain on these buildings may provide data
on their historical evolution and ...
Tracking immune correlates of protection foremerging SARSCoV- 2 variants
(www.thelancet.com/infection, 2023-02-23)
Here we report a proof of concept for monitoring variant-specific SARS-CoV-2 COP using existing surveillance infrastructure in the Dominican Republic. However, global networks of acute febrile illness, influenza-like ...
La formación universitaria en tiempos de COVID – 19. Caso de estudio: República Dominicana
(Editora Artemis, 2023-10-10)
La sociedad ha pasado un momento de ruptura en todas sus esferas: social, económica, política, educativa, etc. generado por la pandemia del COVID – 19. Para la educación significó un cierre total y un cambio en la forma ...
FMNL2 regulates gliovascular interactions and is associated with vascular risk factors and cerebrovascular pathology in Alzheimer’s disease
(Acta Neuropathologica (2022) 144:59–79, 2022-05-24)
Alzheimer’s disease (AD) has been associated with cardiovascular and cerebrovascular risk factors (CVRFs) during middle
age and later and is frequently accompanied by cerebrovascular pathology at death. An interaction ...