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Latin American initiative for lifestyle intervention to prevent cognitive decline (LatAm-FINGERS): study design and harmonization

dc.contributor.authorCrivelli, Lucia
dc.contributor.authorCalandri, Luis
dc.contributor.authorKimie Suemoto, Claudia
dc.contributor.authorSalinas, Rosa María
dc.contributor.authorVelilla, Lina Marcela
dc.contributor.authorSanches Yassuda, Mônica
dc.contributor.authorCaramelli, Paulo
dc.contributor.authorLopera, Francisco
dc.contributor.authorNitrini, Ricardo
dc.contributor.authorSevlever, Gustavo Emilio
dc.contributor.authorSosa, Ana Luisa
dc.contributor.authorAcosta, Daisy
dc.contributor.authorCharamelo Baietti, Ana María
dc.contributor.authorCusicanqui, María Isabel
dc.contributor.authorCustodio, Nilton
dc.contributor.authorDe Simone, Sergio Dansilio
dc.contributor.authorDelgado Derio, Carolina
dc.contributor.authorDuque-Peñailillo, Lissette
dc.contributor.authorDuran, Juan Carlos
dc.contributor.authorJiménez-Velázquez, Ivonne Z.
dc.contributor.authorLeon-Salas, Jorge Mario
dc.contributor.authorBergamo, Yanina
dc.contributor.authorFlorencia Clarens, María
dc.contributor.authorDamian, Andrés
dc.contributor.authorDemey, Ignacio
dc.contributor.authorBelén Helou, María
dc.contributor.authorMárquez, Carlos
dc.contributor.authorMartin, María Eugenia
dc.contributor.authorMorais Martin, Maria da Graça
dc.contributor.authorQuerze, Diego
dc.contributor.authorSurace, Ezequiel Ignacio
dc.contributor.authorAcosta-Egea, Sabrina
dc.contributor.authorAguirre–Salvador, Esteban
dc.contributor.authorda Cunha Peixoto Cançado, Gustavo Henrique
dc.contributor.authorDozzi Brucki
dc.contributor.authorDozzi Brucki, Sonia Maria
dc.contributor.authorVasconcelos Friedlaender, Clarisse
dc.contributor.authorBraga Gomes, Karina
dc.contributor.authorGutierrez, Myriam
dc.contributor.authorLaforcada Ríos, Carlos
dc.contributor.authorMartinez Galindo, Joyce Graciela
dc.contributor.authorMontesinos, Rosa
dc.contributor.authorNuñez-Herrera, Alberto
dc.contributor.authorOspina-Henao, Sebastián
dc.contributor.authorRodríguez, Guillermina
dc.contributor.authorRuiz Masson, Victoria
dc.contributor.authorSánchez, Mónica
dc.contributor.authorChristian E. Schenk, Christian
dc.contributor.authorSoto, Ligia
dc.contributor.authorTonidandel Barbosa, Maira
dc.contributor.authorGonçalves Tosatti, Jéssica Abdo
dc.contributor.authorVicuña, Yosselin
dc.contributor.authorEspeland, Mark
dc.contributor.authorHakansson, Krister
dc.contributor.authorKivipelto, Miia
dc.contributor.authorBaker, Laura
dc.contributor.authorSnyder, Heather
dc.contributor.authorCarrillo, María
dc.contributor.authorAllegri, Ricardo Francisco
dc.date.accessioned2023-09-04T00:43:09Z
dc.date.available2023-09-04T00:43:09Z
dc.date.issued2023-05-19
dc.identifier.citationCrivelli L, Calandri IL, Suemoto CK, Salinas RM, Velilla LM, Yassuda MS, Caramelli P, Lopera F, Nitrini R, Sevlever GE, Sosa AL, Acosta D, Baietti AMC, Cusicanqui MI, Custodio N, De Simone SD, Derio CD, Duque-Peñailillo L, Duran JC, Jiménez-Velázquez IZ, Leon-Salas JM, Bergamo Y, Clarens MF, Damian A, Demey I, Helou MB, Márquez C, Martin ME, Martin MDGM, Querze D, Surace EI, Acosta-Egea S, Aguirre-Salvador E, de Souza LC, Cançado GHDCP, Brucki SMD, Friedlaender CV, Gomes KB, Gutierrez M, Ríos CL, Galindo JGM, Montesinos R, Nuñez-Herrera A, Ospina-Henao S, Rodríguez G, Masson VR, Sánchez M, Schenk CE, Soto L, Barbosa MT, Tosatti JAG, Vicuña Y, Espeland M, Hakansson K, Kivipelto M, Baker L, Snyder H, Carrillo M, Allegri RF. Latin American Initiative for Lifestyle Intervention to Prevent Cognitive Decline (LatAm-FINGERS): Study design and harmonization. Alzheimers Dement. 2023 May 19. doi: 10.1002/alz.13101. Epub ahead of print. PMID: 37204054.en_US
dc.identifier.urihttps://repositorio.unphu.edu.do/handle/123456789/5269
dc.description.abstractLatin American Initiative for Lifestyle Intervention to Prevent Cognitive Decline (LatAm-FINGERS) is the first non-pharmacological multicenter randomized clinical trial (RCT) to prevent cognitive impairment in Latin America (LA). Our aim is to present the study design and discuss the strategies used for multicultural harmonization. This 1-year RCT (working on a 1-year extension) investigates the feasibility of a multi-domain lifestyle intervention in LA and the efficacy of the intervention, primarily on cognitive function. An external harmonization process was carried out to follow the FINGER model, and an internal harmonization was performed to ensure this study was feasible and comparable across the 12 participating LA countries. Currently, 1549 participants have been screened, and 815 randomized. Participants are ethnically diverse (56% are Nestizo) and have high cardiovascular risk (39% have metabolic syndrome). LatAm-FINGERS overcame a significant challenge to combine the region's diversity into a multi-domain risk reduction intervention feasible across LA while preserving the original finger design.en_US
dc.language.isoenen_US
dc.publisherAlzheimer's Association®en_US
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectDemenciaen_US
dc.subjectEnfermedad de Alzheimeren_US
dc.titleLatin American initiative for lifestyle intervention to prevent cognitive decline (LatAm-FINGERS): study design and harmonizationen_US
dc.typeArticleen_US


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