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Molecular Processing of Tau Protein in Progressive Supranuclear Palsy: Neuronal and Glial Degeneration
(IOS Press BV, 2021)Alzheimer's disease (AD) and progressive supranuclear palsy (PSP) are examples of neurodegenerative diseases, characterized by abnormal tau inclusions, that are called tauopathies. AD is characterized by highly insoluble ... -
Monitoring temporal changes in SARS-CoV-2 spike antibody levels and variant-specific risk for infection, Dominican Republic, March 2021–August 2022
(RESEARCH, 2023)To assess changes in SARS-CoV-2 spike binding antibody prevalence in the Dominican Republic and implications for immunologic protection against variants of concern, we prospectively enrolled 2,300 patients with undif ... -
Morphological and fractal properties of brain tumors
(Frontiers in Physiology, 2022-06-27)Tumor interface dynamics is a complex process determined by cell proliferation and invasion to neighboring tissues. Parameters extracted from the tumor interface fluctuations allow for the characterization of the particular ... -
Mortality Rates and Mortality Risk Factors in Older Adults with Dementia from Low- and Middle-Income Countries: The 10/66 Dementia Research Group Population-Based Cohort Study
(Journal of Alzheimer’s Disease 75 (2020) 581–593, 2020-03-09)Background: Dementia is the main cause of disability in older people living in low- and middle-income countries (LMIC). Monitoring mortality rates and mortality risk factors in people with dementia (PwD) may contribute ... -
Mössbauer and X-ray fluorescence study of sediments from Samana Bay, Dominican Republic
(Journal of Radioanalytical and Nuclear Chemistry, 1995-08)The chemical state of iron in sediments collected from Samana Bay has been determined by Mössbauer spectroscopy. The Mössbauer spectra were composed of two paramagnetic doulets, which correspond to high=spin ferric and ... -
Mössbauer study on indigenous ceramics in La Isabela City, Dominican Republic
(Springer Link, 1990)The following study deals with the determination of the firing temperature of some of the ceramics found in La Isabela City, Dominican Republic, first settlement of the Spaniards in the New World. These ceramics were ... -
Multifractal analysis of brain tumor interface in glioblastoma
(PulbMed, 2024)The dynamics of tumor growth is a very complex process, generally accompanied by numerous chromosomal aberrations that determine its genetic and dynamical heterogeneity. Consequently, the tumor interface exhibits a non-regular ... -
Multiple unhealthy behaviors share equivalent profiles of readiness for change in patients with type 2 Diabetes
(International Journal of Environmental Research and Public Health, 2021-03-31)Few studies have considered more than one behavior, despite the tendency towards multiple behaviors, and there are none that have focused on a Latino population. We determined the concurrence of four unhealthy behaviors ... -
Mutations in CYP11B1 gene: phenotype-genotype correlations
(Am J Med Genet A ., 2003-10)11beta-hydroxylase deficiency, an autosomal recessive disorder, is the second most common cause of congenital adrenal hyperplasia. We studied four subjects with classic 11beta-hydroxylase deficiency and severe hypertension: ... -
The Nairobi Declaration—Reducing the burden of dementia in low- and middle-income countries (LMICs): Declaration of the 2022 Symposium on Dementia and Brain Aging in LMICs
(Alzheimer's Association, 2023-03-11)Delegates of the 2022 Symposium on Dementia and Brain Aging in Low- and Middle-Income Countries, representing over 40 countries, met in Nairobi, Kenya, December 5–9 to highlight advances in dementia prevention, diagnosis, ... -
Natural disasters
(2019)Natural disasters can cause a rupture of the daily routine with an essential impact on the local resources and the standard functionality of the population. It is critical that as health care personnel, we are familiar ... -
Neighbourhood environment and dementia in older people from high-, middle- and low-income countries: results from two population-based cohort
(BMC Public Health, 2020)A growing number of studies have explored how features of the neighbourhood environment can be related to cognitive health in later life. Yet few have focused on low- and middle-income countries and compared the results ... -
Neurovascular dysfunction and vascular amyloid accumulation as early events in Alzheimer's disease
(Metabolic Brain Disease, 2021-07)Alzheimer's disease (AD) is clinically characterized by a progressive loss of cognitive functions and short-term memory. AD patients present two distinctive neuropathological lesions: neuritic plaques and neurofibrillary ... -
Neurovascular dysfunction and vascular amyloid accumulation as early events in Alzheimer's disease
(Metabolic Brain Disease, 2021-07)Alzheimer's disease (AD) is clinically characterized by a progressive loss of cognitive functions and short-term memory. AD patients present two distinctive neuropathological lesions: neuritic plaques and neurofibrillary ... -
The neurovascular unit dysfunction in Alzheimer’s disease
(International Journal o f Molecular Sciences, 2021-02-16)Alzheimer’s disease (AD) is the most common neurodegenerative disease worldwide. Histopathologically, AD presents with two hallmarks: neurofibrillary tangles (NFTs), and aggregates of amyloid peptide (A ) both in the ... -
No association between fish intake and depression in over 15,000 older adults from seven low and middle income countries-the 10/66 study.
(PloS ONE, 2012)Evidence on the association between fish consumption and depression is inconsistent and virtually nonexistent from low- and middle-income countries. Using a standard protocol, we aim to assess the association of fish ... -
Nonextraction treatment of a class II open bite in an adult patient.
(Journal of clinical orthodontics : JCO, 2012) -
A Novel Automatic Quantification Protocol for Biomarkers of Tauopathies in the Hippocampus and Entorhinal Cortex of Post-Mortem Samples Using an Extended Semi-Siamese U-Net
(Biology., 2022-07-28)Efforts have been made to diagnose and predict the course of different neurodegenerative diseases through various imaging techniques. Particularly tauopathies, where the tau polypeptide is a key participant in molecular ... -
A novel mutation of the human luteinizing hormone receptor in 46XY and 46XX sisters.
(Journal of Clinical Endocrinology and Metabolism, 1998)We repor t a novel homozygous mutation of the LH receptor (LHR) gene in three siblings: two 46XY and one 46XX. The 46XY siblings presented with female external genitalia, primary amenorrhea, and lack of breast development. ... -
Overweight and obesity: review and update
(Acta Gastroenterológica Latinoamericana, 2016-06)Obesity is an epidemic with important health repercussions in addition to high treatment-related costs. Between 2006 and 2007 the WHO developed new assessment tools, which aren’t being globally used. In fact, there is no ...
