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Steroid 5α-reductase deficiency in man: An inherited form of male pseudohermaphroditism
dc.contributor.author | Imperato-McGinley, Julianne | |
dc.contributor.author | Guerrero, Luis | |
dc.contributor.author | Gautier, Teofilo | |
dc.contributor.author | Peterson, Ralph E | |
dc.date.accessioned | 2024-08-29T01:54:49Z | |
dc.date.available | 2024-08-29T01:54:49Z | |
dc.date.issued | 1974-12-27 | |
dc.identifier.citation | Imperato-McGinley J, Guerrero L, Gautier T, Peterson RE. Steroid 5alpha-reductase deficiency in man: an inherited form of male pseudohermaphroditism. Science. 1974 Dec 27;186(4170):1213-5. doi: 10.1126/science.186.4170.1213. PMID: 4432067. | en_US |
dc.identifier.issn | 00368075 | |
dc.identifier.uri | https://repositorio.unphu.edu.do/handle/123456789/5851 | |
dc.description.abstract | In male pseudohermaphrodites born with ambiguity of the external genitalia but with marked virilization at puberty, biochemical evaluation reveals a marked decrease in plasma dihydrotestosterone secondary to a decrease in steroid 5alpha-reductase activity. In utero the decrease in dihydrotestosterone results in incomplete masculinization of the external genitalia. Inheritance is autosomal recessive | en_US |
dc.language.iso | en | en_US |
dc.publisher | Science | en_US |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | Organismos hermafroditas | en_US |
dc.subject | Procesos de determinación del sexo | en_US |
dc.title | Steroid 5α-reductase deficiency in man: An inherited form of male pseudohermaphroditism | en_US |
dc.type | Article | en_US |
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