• Mechanistic Insight from Preclinical Models of Parkinson’s Disease Could Help Redirect Clinical Trial Efforts in GDNF Therapy 

      Delgado-Minjares, Karen M.; Martinez-Fong, Daniel; Martínez-Dávila, Irma A.; Bañuelos, Cecilia; Gutierrez-Castillo, M. E.; Blanco-Alvarez, Víctor Manuel; Cardenas-Aguayo, Maria-del-Carmen; Luna-Muñoz, José; Pacheco-Herrero, Mar; Soto-Rojas, Luis O. (Int. J. Mol. Sci, 2021)
      Parkinson’s disease (PD) is characterized by four pathognomonic hallmarks: (1) motor and non-motor deficits; (2) neuroinflammation and oxidative stress; (3) pathological aggregates of the α-synuclein (α-syn) protein; (4) ...