Listar Artículos por autor "Lantigua, Rafael A."

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    • Evaluation of Plasma Biomarkers for A/T/N Classification of Alzheimer Disease Among Adults of Caribbean Hispanic Ethnicity 

      Honig, Lawrence S; Suk Kang, Min; Lee, Annie J.; Reyes-Dumeyer, Dolly; Piriz, Angel; Soriano, Belisa; Domínguez Coronado, Zoraida; Recio, Patricia; Rivera Mejia, Diones; Medrano, Martin; Lantigua, Rafael A.; Teich, Andrew F.; Dage, Jeffrey L.; Mayeux, Richard (JAMA Netw Open., 2023)
      Cerebrospinal fluid (CSF) and plasma biomarkers can detect biological evidence of Alzheimer disease (AD), but their use in low-resource environments and among minority ethnic groups is limited. To assess validated plasma ...

    • FMNL2 regulates gliovascular interactions and is associated with vascular risk factors and cerebrovascular pathology in Alzheimer’s disease 

      Lee, Annie J.; Raghavan, Neha S.; Bhattarai, Prabesh; Siddiqui, Tohid; Sariya, Sanjeev; Reyes‑Dumeyer, Dolly; Flowers, Xena E.; Cardoso, Sarah A. L.; De Jager, Philip L.; Bennett, David A.; Schneider, Julie A.; Menon, Vilas; Wang, Yanling; Lantigua, Rafael A.; Medrano, Martin; Rivera, Diones; Jimenez‑Velazquez, Ivonne Z.; Kukull, Walter A.; Brickman, Adam M.; Manly, Jennifer J.; Tosto, Giuseppe; Kizil, Caghan; Vardarajan, Badri N.; Mayeux, Richard (Acta Neuropathologica (2022) 144:59–79, 2022-05-24)
      Alzheimer’s disease (AD) has been associated with cardiovascular and cerebrovascular risk factors (CVRFs) during middle age and later and is frequently accompanied by cerebrovascular pathology at death. An interaction ...

    • Progranulin mutations in clinical and neuropathological Alzheimer’s disease 

      Vardarajan, Badri N.; Reyes-Dumeyer, Dolly; L. Piriz1, Angel; Lantigua, Rafael A.; Medrano, Martin; Rivera, Diones; Jiménez-Velázquez, Ivonne Z.; Martin, Eden; Pericak-Vance, Margaret A.; Bush, William; Farrer, Lindsay; Haines, Jonathan L.; Wang, Li-San; Yee Leung, Yuk; Schellenberg, Gerard; Kukull, Walter; De Jager, Philip; Bennett, David A.; Schneider, Julie A.; Alzheimer’s Disease Sequencing Project; Mayeux, Richard (Alzheimers Dement., 2022-12-10)
      Progranulin (GRN) mutations occur in frontotemporal lobar degeneration (FTLD) and in Alzheimer’s disease (AD), often with TDP-43 pathology. We determined the frequency of rs5848 and rare, pathogenic GRN mutations in two ...