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Biomarker Candidates for Alzheimer’s Disease Unraveled through In Silico Differential Gene Expression Analysis
(Basel, 2022-05-07)
Alzheimer’s disease (AD) is neurodegeneration that accounts for 60–70% of dementia cases.
Symptoms begin with mild memory difficulties and evolve towards cognitive impairment. The
underlying risk factors remain primarily ...
A Novel Automatic Quantification Protocol for Biomarkers of Tauopathies in the Hippocampus and Entorhinal Cortex of Post-Mortem Samples Using an Extended Semi-Siamese U-Net
(Biology., 2022-07-28)
Efforts have been made to diagnose and predict the course of different neurodegenerative
diseases through various imaging techniques. Particularly tauopathies, where the tau polypeptide
is a key participant in molecular ...
What trauma patients need: the European dilemma
(European Journal of Trauma and Emergency Surgery, 2022-07-22)
There is a need for implementation and maturation of an inclusive trauma system in every country in Europe, with patient centered care by dedicated surgeons. This process should be initiated by physicians and medical ...
Characterization of lime mortar and plasters of Fortress Concepción de la Vega
(MatTech, 2022-06-10)
The arrival of Christopher Columbus in America stimulated the creation of new settlements in which the materials and construction
methods coming from Spain and those existing in the area were used. The first village built ...
Specification, Verification, and Calibration of Active Electronically Scanned Array (AESA) Antennas
(IEEE, 2021)
Active Electronically Scanned Arrays (AESA's) have gained over the last years an increasing interest and utilization, for both space and ground applications. On board satellites, such antennas are often adopted in ...
Psychometry and estimation of cutoff points of Jefferson Scale of empathy in dental students
(Wiley, 2020-10-09)
The objective of this study was to determine the psychometric properties of the 3-dimensional latent model of empathy on the Jefferson Scale of Physician Empathy instrument (version S), and to verify the existence of cutoff ...
Characterization of XVI Century Wall Paint and Lime Mortar in the Façade of the Cathedral of Santo Domingo, Dominican Republic
(Springer Link, 2022)
The Cathedral of Santo Domingo (1521–1541), is the oldest in the New World. The main façade was finished in 1540 by Spanish builders from the Kingdom of Castile, Spain, built with Coralina limestone ashlars joined with ...
Current status and challenges of stem cell treatment for Alzheimer’s disease
(Journal of Alzheimer’s Disease, 2021)
Neurodegenerative diseases called tauopathies, such as Alzheimer’s disease (AD), frontotemporal dementia, progressive supranuclear palsy, and Parkinson’s disease, among others, are characterized by the pathological processing ...
Intravenous tocilizumab in the management of rheumatoid arthritis: Clinical practice findings from a 6-month international, multicentre, observational study in Central America and the Caribbean
(Revista Colombiana de Reumatología, 2020)
Tocilizumab (TCZ), an interleukin-6 receptor-α inhibitor, is indicated in patients with moderate to severe rheumatoid arthritis with inadequate response to disease modifying drugs. ACT UP is a multinational project collecting ...
Decline in empathy levels and sex differences in medical students from the Caribbean
(Semantic Scholar., 2021)
Empathy is an important trait in the training of medical students, as it has been shown that it improves the doctor-patient relationship. To evaluate the decline of empathy levels and possible sex differences in undergraduate ...