Mostrando ítems 81-90 de 125
Burden of Parkinsonism and Parkinson's disease on health service use and outcomes in Latin America
(Journal of Parkinson's Disease, 2023-11-03)
Little is known about the burden of parkinsonism and Parkinson’s disease (PD) in Latin America. Better understanding of health service use and clinical outcomes in PD is needed to improve its prognosis.
The aim of the ...
Mechanistic Insight from Preclinical Models of Parkinson’s Disease Could Help Redirect Clinical Trial Efforts in GDNF Therapy
(Int. J. Mol. Sci, 2021)
Parkinson’s disease (PD) is characterized by four pathognomonic hallmarks: (1) motor
and non-motor deficits; (2) neuroinflammation and oxidative stress; (3) pathological aggregates of
the α-synuclein (α-syn) protein; (4) ...
What trauma patients need: the European dilemma
(European Journal of Trauma and Emergency Surgery, 2022)
There is a need for implementation and maturation of an inclusive trauma system in every country in Europe, with patient centered care by dedicated surgeons. This process should be initiated by physicians and medical ...
Trauma quality improvement program: a retrospective analysis from a middle eastern National Trauma Center
(Healthcare, 2023-10-31)
The Trauma Quality Improvement Program (American College of Surgery
(ACS-TQIP)) uses the existing infrastructure of the Committee on Trauma programs and provides
feedback to participating hospitals on risk-adjusted ...
Physical and Chemical Characterisation of the Pigments of a 17th-Century Mural Painting in the Spanish Caribbean
(MDPI, 2021)
The arrival of Spaniards in the Caribbean islands introduced to the region the practice of
applying pigments onto buildings. The pigments that remain on these buildings may provide data
on their historical evolution and ...
Tracking immune correlates of protection foremerging SARSCoV- 2 variants
(www.thelancet.com/infection, 2023-02-23)
Here we report a proof of concept for monitoring variant-specific SARS-CoV-2 COP using existing surveillance infrastructure in the Dominican Republic. However, global networks of acute febrile illness, influenza-like ...
Exsanguination: reliable models to indicate damage control
(Current Therapy of Trauma and Surgical Critical Care, 2023-01-01)
Exsanguination is a syndrome defined as extreme form of hemorrhage that if not surgically controlled will lead to death. This chapter defines the syndrome and describes the injuries prone to cause this most extreme form ...
FMNL2 regulates gliovascular interactions and is associated with vascular risk factors and cerebrovascular pathology in Alzheimer’s disease
(Acta Neuropathologica (2022) 144:59–79, 2022-05-24)
Alzheimer’s disease (AD) has been associated with cardiovascular and cerebrovascular risk factors (CVRFs) during middle
age and later and is frequently accompanied by cerebrovascular pathology at death. An interaction ...
Comparison of in‑hospital and out‑of‑hospital cardiac arrest of trauma patients in Qatar
(International Journal of Emergency Medicine, 2022)
Cardiac arrests in admitted hospital patients with trauma have not been described in the literature. We
defined “in-hospital cardiac arrest of a trauma” (IHCAT) patient as “cessation of circulatory activity in a trauma ...
Progranulin mutations in clinical and neuropathological Alzheimer’s disease
(Alzheimers Dement., 2022-12-10)
Progranulin (GRN) mutations occur in frontotemporal lobar degeneration
(FTLD) and in Alzheimer’s disease (AD), often with TDP-43 pathology.
We determined the frequency of rs5848 and rare, pathogenic GRN mutations
in two ...