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Drug-induced liver injury: A management position paper from the Latin American Association for Study of the liver
(Annals of Hepatology, 2021)
Idiosyncratic drug-induced liver injury (DILI) caused by xenobiotics (drugs, herbals and dietary supplements)
is an uncommon cause of liver disease presenting with a wide range of phenotypes and
disease severity, acute ...
Identification of Rgp1p, a novel Golgi recycling factor, as a protein required for efficient localization of yeast casein kinase 1 to the plasma membrane
(Journal of Cell Science, 2000)
The Yck1p and Yck2p casein kinase 1 isoforms in yeast are essential peripheral plasma membrane-associated protein kinases with roles in endocytosis, cellular morphogenesis and cytokinesis. The membrane targeting of these ...
Ingol diterpene ester from the latex of Euphorbia lactea
(Fitoterapia, 1999-04)
The stereochemistry of the ingol diterpene 3,12-di-O-acetyl-8-O-tigloyl-ingol (1), isolated from the latex of Euphorbia lactea, was determined by one- and two-dimensional NMR analysis.
Burden of Parkinsonism and Parkinson's disease on health service use and outcomes in Latin America
(Journal of Parkinson's Disease, 2023-11-03)
Little is known about the burden of parkinsonism and Parkinson’s disease (PD) in Latin America. Better understanding of health service use and clinical outcomes in PD is needed to improve its prognosis.
The aim of the ...
Mechanistic Insight from Preclinical Models of Parkinson’s Disease Could Help Redirect Clinical Trial Efforts in GDNF Therapy
(Int. J. Mol. Sci, 2021)
Parkinson’s disease (PD) is characterized by four pathognomonic hallmarks: (1) motor
and non-motor deficits; (2) neuroinflammation and oxidative stress; (3) pathological aggregates of
the α-synuclein (α-syn) protein; (4) ...
What trauma patients need: the European dilemma
(European Journal of Trauma and Emergency Surgery, 2022)
There is a need for implementation and maturation of an inclusive trauma system in every country in Europe, with patient centered care by dedicated surgeons. This process should be initiated by physicians and medical ...
Trauma quality improvement program: a retrospective analysis from a middle eastern National Trauma Center
(Healthcare, 2023-10-31)
The Trauma Quality Improvement Program (American College of Surgery
(ACS-TQIP)) uses the existing infrastructure of the Committee on Trauma programs and provides
feedback to participating hospitals on risk-adjusted ...
Physical and Chemical Characterisation of the Pigments of a 17th-Century Mural Painting in the Spanish Caribbean
(MDPI, 2021)
The arrival of Spaniards in the Caribbean islands introduced to the region the practice of
applying pigments onto buildings. The pigments that remain on these buildings may provide data
on their historical evolution and ...
Tracking immune correlates of protection foremerging SARSCoV- 2 variants
(www.thelancet.com/infection, 2023-02-23)
Here we report a proof of concept for monitoring variant-specific SARS-CoV-2 COP using existing surveillance infrastructure in the Dominican Republic. However, global networks of acute febrile illness, influenza-like ...
Hypertension prevalence, awareness, treatment and control among older people in Latin America, India and China: a 10/66 cross-sectional population-based survey
(J Hypertens ., 2012)
To estimate the prevalence, social patterning, treatment and control of hypertension among older people in the 10/66 Dementia Research Group developing country sites. Cross-sectional surveys of SBP, hypertension, and ...