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Missense and loss-of-function variants at GWAS loci in familial Alzheimer's disease
(Alzheimer's and Dementia, 2024)Few rare variants have been identified in genetic loci from genome-wide association studies (GWAS) of Alzheimer's disease (AD), limiting understanding of mechanisms, risk assessment, and genetic counseling. Using genome ... -
Convergence of SARS-CoV-2 spike antibody levels to a population immune setpoint
(eBioMedicine, 2024)Individual immune responses to SARS-CoV-2 are well-studied, while the combined effect of these responses on population-level immune dynamics remains poorly understood. Given the key role of population immunity on pathogen ... -
Work route for the inclusion of learning analytics in the development of interactive multimedia experiences for elementary education
(Apply Sciences, 2024-08-29)Interactive multimedia experiences (IME) can be a pedagogical resource that has a strong potential to enhance learning experiences in early childhood. Learning analytics (LA) has become an important tool that allows us ... -
Longitudinal changes in hand hygiene adherence among healthcare workers during the COVID-19 pandemic, Dominican Republic
(PLOS Water, 2024-05-24)Hand hygiene (HH) can reduce transmission of healthcare-associated infections (HAIs) in healthcare facilities and is especially important in low- and middle-income countries where HH infrastructure may be insufficient ... -
Relationship between problematic Internet use and depression in young Latin American College students
(Behavioral Sciences 2024, 14, 719., 2024-08-16)Problematic Internet use (PIU) in young people is a topic of great interest both in the field of addictions and mental health, but scientific evidence is limited in Latin America. The aim was to analyze the relationship ... -
Cross-sectional and prospective associations between Parkinsonism and Parkinson's disease with frailty in Latin America
(Movement Disorders Clinical Practice, 2024)Little is known about the relationship between parkinsonism or Parkinson's disease (PD) and frailty in Latin America.The study aimed to determine the cross-sectional and prospective associations between parkinsonism and ... -
Epigenetic and genetic risk of Alzheimer disease from autopsied brains in two ethnic groups
(Acta Neuropathologica (2024) 148:27, 2024-08-01)Genetic variants and epigenetic features both contribute to the risk of Alzheimer’s disease (AD). We studied the AD association of CpG-related single nucleotide polymorphisms (CGS), which act as a hub of both the genetic ... -
Construction of a bite plane with light-cured resin.
(Journal of clinical orthodontics : JCO, 1993) -
MtDNA from extinct Tainos and the peopling of the Caribbean
(Annals of Human Genetics, 2001)Tainos and Caribs were the inhabitants of the Caribbean when Columbus reached the Americas; both human groups became extinct soon after contact, decimated by the Spaniards and the diseases they brought. Samples belonging ... -
Associations between education and dementia in the caribbean and the United States: An international comparison
(Alzheimer's and Dementia: Translational Research and Clinical Interventions, 2021)Despite high dementia prevalence in Hispanic populations globally, especially Caribbean Hispanics, no study has comparatively examined the association between education and dementia among Hispanics living in the Caribbean ... -
The molecular basis of steroid 5α-reductase deficiency in a large dominican kindred
(New England Journal of Medicine, 1992)PSEUDOHERMAPHRODITISM in men is often caused by genetic deficiencies in the production or action of androgens.1 , 2 One form of this condition is a deficiency of steroid 5α-reductase, the enzyme that catalyzes the conversion ... -
Cofradías de esclavos negros, morenos y mulatos libres en la Catedral de Santo Domingo, Primada de AméricaBlacks slaves, browns and free mulattoes confraternities in the Cathedral of Santo Domingo, Primate of America
(Anuario de Historia de la Iglesia, 2021)The evangelization of the indigenous and spiritual assistance to the colonizers and Creoles, was a priority in the conquest and colonization of the Indies. The black slave was also evangelized but with different strategies, ... -
Determination of potassium and calcium in milk powder by energy‐dispersive x‐ray fluorescence spectrometry
(X‐Ray Spectrometry, 1990-12)A rapid method for the simultaneous determination of potassium and calcium in milk powder by energy‐dispersive x‐ray fluorescence (EDXRF) spectrometry was developed. The measurement system consists of a Si(Li) detector, ... -
Conversion electron Mössbauer spectra of non-conducting samples
(Journal of Radioanalytical and Nuclear Chemistry Articles, 1989-10)For this work, a parallel plate avalanche counter was used, filled with ketone gas within the ionization chamber, to obtain CEM spectra for non-conducting samples: α-Fe2O3, Fe3O4, Fe(NH4)2(SO4)2·6H2O, and a mineral sample ... -
Effect of GNSS on-board and user antennas phase center calibration on high accuracy positioning applications
(FGM Events LLC, 2019)The paper reviews the impacts of satellite and user antenna PCO’s and PCV’s on positioning accuracy, with special attention to high accuracy applications, such as geodetic mapping and infrastructures surveying by UAV’s. -
The art of healing in the era of emerging technologies: Back to the fundamentals of clinical medicine
(JEMTAC, 2023-08-30)The incorporation of innovative technology at the bedside is expediting the evaluation and diagnosis of patients during the clinical practice of medicine, surgery, and sub-specialties such as trauma surgery, emergency ... -
Male pseudohermaphroditism due to steroid 5-alpha-reductase deficiency
(PublMed, 1977)A new inherited form of male pseudohermaphroditism has been investigated in a pedigree of 24 families with 38 affected males. At birth, the affected males (46 XY) have a clitoral-like phallus, bifid scrotum and urogenital ... -
The diagnosis of 5α-reductase deficiency in infancy
(Journal of Clinical Endocrinology and Metabolism, 1986-12)The diagnosis of 5α-reductase deficiency in infancy is reported for the first timein three male pseudohermaphrodites from the Dominican Republic. Basal plasma testosterone to dihydrotestosterone ratios were significantly ... -
Prevalence of antibodies to the human immunodeficiency virus in dominicans and haitians in the Dominican Republic.
(JAMA, 1987)Few patients with the acquired immunodeficiency syndrome have been reported in the Dominican Republic, although they share the island of Hispaniola with Haiti, which has numerous cases. Prevalence of antibodies to the human ... -
Steroid 5α-reductase deficiency in man: An inherited form of male pseudohermaphroditism
(Science, 1974-12-27)In male pseudohermaphrodites born with ambiguity of the external genitalia but with marked virilization at puberty, biochemical evaluation reveals a marked decrease in plasma dihydrotestosterone secondary to a decrease in ...
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