• Elucidating the neuropathologic mechanisms of SARS-cov-2 infection. 

      Pacheco Herrero, Mar; Soto Rojas, Luis O.; Harrington, Charles R.; Flores Martínez, Yazmín M.; Villegas Rojas, Marcos M.; León Aguilar, Alfredo M.; Martínez Gómez, Paola A.; Campa Córdoba, B. Berenice; Apátiga Pérez, Ricardo; Corniel Taveras, Carolin N.; Domínguez García, Jesabelle de J.; Blanco Alvarez, Víctor Manuel; Luna Muñoz, José (Frontiers in Neurology, 2021-04-12)
      The current pandemic caused by the new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a public health emergency. To date, March 1, 2021, coronavirus disease 2019 (COVID-19) has caused about 114 ...
    • Insoluble vascular amyloid deposits trigger disruption of the neurovascular unit in Alzheimer’s disease brains. 

      Soto Rojas, Luis O.; Campa Córdoba, Berenice; Harrington, Charles R.; Salas Casas, Andrés; Hernandes Alejandro, Mario; Villanueva Fierro, Ignacio; Bravo Muñoz, Marely; Garcés Ramírez, Linda; Cruz López, Fidel de la; Ontiveros Torres, Miguel Ángel; Gevorkian, Goar; Pacheco Herrero, Mar; Luna Muñoz, José (Int. J. Mol. Sci, 2021-04-01)
      Alzheimer’s disease (AD) is a neurodegenerative disease, characterized histopathologically by intra-neuronal tau-related lesions and by the accumulation of amyloid -peptide (A ) in the brain parenchyma and around cerebral ...
    • Molecular Processing of Tau Protein in Progressive Supranuclear Palsy: Neuronal and Glial Degeneration 

      Martínez-Maldonado, Alejandra; Ontiveros-Torres, Miguel Ángel; Harrington, Charles R.; Montiel-Sosa, José Francisco; Prandiz, Raúl García Tapia; Bocanegra-López, Patricia; Sorsby-Vargas, Andrew Michael; Bravo-Muñoz, Marely; Florán-Garduño, Benjamín; Villanueva-Fierro, Ignacio; Perry, George; Garcés-Ramírez, Linda; de la Cruz, Fidel; Martínez-Robles, Sandra; Pacheco-Herrero, Mar; Luna-Muñoz, José (IOS Press BV, 2021)
      Alzheimer's disease (AD) and progressive supranuclear palsy (PSP) are examples of neurodegenerative diseases, characterized by abnormal tau inclusions, that are called tauopathies. AD is characterized by highly insoluble ...
    • The neurovascular unit dysfunction in Alzheimer’s disease 

      Soto-Rojas, Luis O.; Pacheco-Herrero, Mar; Martínez-Gómez, Paola A.; Campa-Córdoba, B. Berenice; Apátiga-Pérez, Ricardo; Villegas-Rojas, Marcos M.; Harrington, Charles R.; Cruz, Fidel de la; Garcés-Ramírez, Linda; Luna-Muñoz, José (International Journal o f Molecular Sciences, 2021-02-16)
      Alzheimer’s disease (AD) is the most common neurodegenerative disease worldwide. Histopathologically, AD presents with two hallmarks: neurofibrillary tangles (NFTs), and aggregates of amyloid peptide (A ) both in the ...
    • Tau protein phosphorylated at threonine-231 is expressed abundantly in the cerebellum in prion encephalopathies. 

      Gómez López, Víctor Manuel; Viramontes Pintos, Amparo; Ontiveros Torres, Miguel Ángel; Garcés Ramírez, Linda; Cruz López, Fidel de la; Villanueva Fierro, Ignacio; Bravo Muñoz, Marely; Harrington, Charles R.; Martínez Robles, Sandra; Yescas, Petra; Guadarrama Ortíz, Parménides; Hernándes Alejandro, Mario; Montiel Sosa, Francisco; Pacheco Herrero, Mar; Luna Muñoz, José (Journal of Alzheimer’s Disease, 2021-04-02)
      Transmissible spongiform encephalopathies (TSEs) are rare neurodegenerative disorders that affect animals and humans. Bovine spongiform encephalopathy (BSE) in cattle, and Creutzfeld-Jakob Disease (CJD) in humans belong to ...