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Ingol diterpene ester from the latex of Euphorbia lactea
(Fitoterapia, 1999-04)The stereochemistry of the ingol diterpene 3,12-di-O-acetyl-8-O-tigloyl-ingol (1), isolated from the latex of Euphorbia lactea, was determined by one- and two-dimensional NMR analysis. -
Inherited 5α-reductase deficiency in man
(ScienceDirect, 1986)Study of the syndrome of 5α-reductase deficiency in man has elucidated the importance of testosterone conversion to dihydrotestosterone in sexual differentiation of the male fetus. Insights into specific actions for ... -
Insoluble vascular amyloid deposits trigger disruption of the neurovascular unit in Alzheimer’s disease brains.
(Int. J. Mol. Sci, 2021-04-01)Alzheimer’s disease (AD) is a neurodegenerative disease, characterized histopathologically by intra-neuronal tau-related lesions and by the accumulation of amyloid -peptide (A ) in the brain parenchyma and around cerebral ... -
Interpretable Classification of Tauopathies with a Convolutional Neural Network Pipeline Using Transfer Learning and Validation against Post-Mortem Clinical Cases of Alzheimer’s Disease and Progressive Supranuclear Palsy
(MDP, 2022-11-22)Neurodegenerative diseases, tauopathies, constitute a serious global health problem. The etiology of these diseases is unclear and an increase in their incidence has been projected in the next 30 years. Therefore, the ... -
Intragastric balloon
(Springer Link, 2016)Obesity is a serious, complex disease and both its treatment and management have remained a global medical challenge. It has been proven that obesity reduces the quality of life as well as life expectancy in patients and ... -
Intravenous tocilizumab in the management of rheumatoid arthritis: Clinical practice findings from a 6-month international, multicentre, observational study in Central America and the Caribbean
(Revista Colombiana de Reumatología, 2020)Tocilizumab (TCZ), an interleukin-6 receptor-α inhibitor, is indicated in patients with moderate to severe rheumatoid arthritis with inadequate response to disease modifying drugs. ACT UP is a multinational project collecting ... -
Intrinsic capacity and its associations with incident dependence and mortality in 10/66 Dementia Research Group studies in Latin America, India, and China: A population-based cohort study
(Plos Medicine, 2021)The World Health Organization (WHO) has reframed health and healthcare for older people around achieving the goal of healthy ageing. The recent WHO Integrated Care for Older People (ICOPE) guidelines focus on maintaining ... -
The Jefferson scale of empathy: measurement properties, underlying components, norms, and cutoff points in dentistry students in latin america. A multicentric study.
(Interciencia, 2021-05-07)The empathy observed by practicing health professionals is the product of the quality of empathic training received from the beginning of their studies. Such training is a problem that must be considered from the early ... -
Latin America intensive care unit disaster preparedness: results from a web‑based attitudes and perceptions survey
(International Journal of Critical Illness and Injury Science | Published by Wolters Kluwer - Medknow, 2019-11-11)Disasters burden on hospital emergency intensive care units (ICUs). This burden is increased in Latin America (LATAM) where hospital resources, intrahospital disaster simulations, and perceived level of preparedness vary ... -
Latin American anaphylaxis registry
(Elsevier Inc. on behalf of World Allergy Organization., 2023-01-23)Recent data about clinical features, triggers and management of anaphylaxis in Latin America is lacking. To provide updated and extended data on anaphylaxis in this region. An online questionnaire was used, with 67 ... -
Latin American Association for the study of the liver recommendations on treatment of Hepatitis C
(Annals of Hepatology, 2014-08)The following recommendations provide an approach to the establishment of guidelines for the diagnosis, management, and treatment of hepatitis C virus infection. These guidelines are based on a formal analysis and review ... -
Latin American initiative for lifestyle intervention to prevent cognitive decline (LatAm-FINGERS): study design and harmonization
(Alzheimer's Association®, 2023-05-19)Latin American Initiative for Lifestyle Intervention to Prevent Cognitive Decline (LatAm-FINGERS) is the first non-pharmacological multicenter randomized clinical trial (RCT) to prevent cognitive impairment in Latin America ... -
Learnings from real-life experience of using omalizumab for chronicurticaria in Latin America
(Elsevier, 2019-01-08)Updated urticaria guidelines recommend that patients should be assessed for disease activity, severity, control, and quality of life at baseline and follow up. Regarding treatment, guidelines consider second generation ... -
Leg length, skull circumference, and the incidence of dementia in Latin America and China: a 10/66 population-based cohort study
(PLOS ONE, 2018-04-18)Adult leg length is influenced by nutrition in the first few years of life. Adult head circumference is an indicator of brain growth. Cross-sectional studies indicate inverse associations with dementia risk, but there ... -
Levels of chlorinated hydrocarbons and trace metals in bivalves and nearshore sediments from the Dominican Republic
(Marine Pollution Bulletin, 1998-12)Bivalves (Crassostrea rizhophorae, Isognomon alatus, Codakia orbicularis Linné, and Tellina fausta) and sediment samples collected from 12 locations along the Dominican Republic coastline were used to assess the degree of ... -
Liver injury after methylprednisolone pulses: A disputable cause of hepatotoxicity. A case series and literature review
(United European Gastroenterology Journal, 2019-02-17)Corticosteroids are often empirically used to treat idiosyncratic hepatotoxicity with severe features. Interestingly, intravenous methylprednisolone (MP) is increasingly being recognized as being responsible for liver ... -
Loneliness among older adults in Latin America, China, and India: prevalence, correlates and association with mortality
(International Journal of Public Health, 2021-03)This study was designed to explore prevalence and correlates of selfreported loneliness and to investigate whether loneliness predicts mortality among older adults (aged 65 or above) in Latin America, China and India. The ... -
Long-term growth hormone therapy in adulthood results in significant linear growth in siblings with a PROP-1 gene mutation.
(Journal of Clinical Endocrinology and Metabolism, 2004)PROP-1 g ene mutations result in impaired production of GH, gonadotropins, TSH, and prolactin. We describe three adult siblings, aged 18-25 yr, with short stature, hypothyroidism, and lack of pubertal maturation, who were ... -
Long-term stability of two-phase class II: treatment with the carriere motion appliance
(Journal of Clinical Orthodontics, 2019-08) -
A low-cost LN2 monitor
(American Journal of Physician, 1989)