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Mechanistic Insight from Preclinical Models of Parkinson’s Disease Could Help Redirect Clinical Trial Efforts in GDNF Therapy
(Int. J. Mol. Sci, 2021)
Parkinson’s disease (PD) is characterized by four pathognomonic hallmarks: (1) motor
and non-motor deficits; (2) neuroinflammation and oxidative stress; (3) pathological aggregates of
the α-synuclein (α-syn) protein; (4) ...
What trauma patients need: the European dilemma
(European Journal of Trauma and Emergency Surgery, 2022)
There is a need for implementation and maturation of an inclusive trauma system in every country in Europe, with patient centered care by dedicated surgeons. This process should be initiated by physicians and medical ...
Trauma quality improvement program: a retrospective analysis from a middle eastern National Trauma Center
(Healthcare, 2023-10-31)
The Trauma Quality Improvement Program (American College of Surgery
(ACS-TQIP)) uses the existing infrastructure of the Committee on Trauma programs and provides
feedback to participating hospitals on risk-adjusted ...
Physical and Chemical Characterisation of the Pigments of a 17th-Century Mural Painting in the Spanish Caribbean
(MDPI, 2021)
The arrival of Spaniards in the Caribbean islands introduced to the region the practice of
applying pigments onto buildings. The pigments that remain on these buildings may provide data
on their historical evolution and ...
Tracking immune correlates of protection foremerging SARSCoV- 2 variants
(www.thelancet.com/infection, 2023-02-23)
Here we report a proof of concept for monitoring variant-specific SARS-CoV-2 COP using existing surveillance infrastructure in the Dominican Republic. However, global networks of acute febrile illness, influenza-like ...
FMNL2 regulates gliovascular interactions and is associated with vascular risk factors and cerebrovascular pathology in Alzheimer’s disease
(Acta Neuropathologica (2022) 144:59–79, 2022-05-24)
Alzheimer’s disease (AD) has been associated with cardiovascular and cerebrovascular risk factors (CVRFs) during middle
age and later and is frequently accompanied by cerebrovascular pathology at death. An interaction ...
Comparison of in‑hospital and out‑of‑hospital cardiac arrest of trauma patients in Qatar
(International Journal of Emergency Medicine, 2022)
Cardiac arrests in admitted hospital patients with trauma have not been described in the literature. We
defined “in-hospital cardiac arrest of a trauma” (IHCAT) patient as “cessation of circulatory activity in a trauma ...
Progranulin mutations in clinical and neuropathological Alzheimer’s disease
(Alzheimers Dement., 2022-12-10)
Progranulin (GRN) mutations occur in frontotemporal lobar degeneration
(FTLD) and in Alzheimer’s disease (AD), often with TDP-43 pathology.
We determined the frequency of rs5848 and rare, pathogenic GRN mutations
in two ...
Direct healthcare costs of moderate and severe work-related injuries: estimates from the National Trauma Center of Qatar
(International Journal of Environmental Research and Public Health, 2022-01-30)
Work-related injuries (WRIs) are recognized as a leading cause of admission to the national
trauma center of Qatar. A retrospective analysis of trauma registry data and electronic medical
records was conducted on a cohort ...
Empathy in Professors and Students of a School of Dentistry in the Caribbean
(Pesquisa Brasileira em Odontopediatria e Clínica Integrada, 2022-07-29)
To estimate and compare the levels of empathy between undergraduate dentistry students and
professors at a university in the Dominican Republic. Material and Methods: Cross-sectional and
descriptive study. The studied ...