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Mechanistic Insight from Preclinical Models of Parkinson’s Disease Could Help Redirect Clinical Trial Efforts in GDNF Therapy
(Int. J. Mol. Sci, 2021)
Parkinson’s disease (PD) is characterized by four pathognomonic hallmarks: (1) motor
and non-motor deficits; (2) neuroinflammation and oxidative stress; (3) pathological aggregates of
the α-synuclein (α-syn) protein; (4) ...
Physical and Chemical Characterisation of the Pigments of a 17th-Century Mural Painting in the Spanish Caribbean
(MDPI, 2021)
The arrival of Spaniards in the Caribbean islands introduced to the region the practice of
applying pigments onto buildings. The pigments that remain on these buildings may provide data
on their historical evolution and ...
Climate change and global issues in allergy and immunology
(J ALLERGY CLIN IMMUNO, 2021)
The steady increase in global temperatures, resulting from the combustion of fossil fuels and the accumulation of greenhouse gases (GHGs), continues to destabilize all ecosystems worldwide. Although annual emissions must ...