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Intrinsic capacity and its associations with incident dependence and mortality in 10/66 Dementia Research Group studies in Latin America, India, and China: A population-based cohort study
(Plos Medicine, 2021)
The World Health Organization (WHO) has reframed health and healthcare for older people
around achieving the goal of healthy ageing. The recent WHO Integrated Care for Older
People (ICOPE) guidelines focus on maintaining ...
Correction to: Patterns and Effects of Admission Hyperglycemia and Inflammatory Response in Trauma Patients: A Prospective Clinical Study
(World J Surg, 2021)
The constellation of the initial hyperglycemia, proinflammatory cytokines and severity of injury among
trauma patients is understudied. We aimed to evaluate the patterns and effects of on-admission hyperglycemia and ...
Work-related injuries in Qatar for 1 year: an initial report from the work-related injury unified registry for Qatar
(Qatar Medical Journal, 2022)
The Ministry of Public Health National Health Strategy 2018 – 2022 has recognized the need for accurate, updated, and representative data that truly reflects the occupational health and safety status in Qatar. In 2015, the ...
Drug-induced liver injury: A management position paper from the Latin American Association for Study of the liver
(Annals of Hepatology, 2021)
Idiosyncratic drug-induced liver injury (DILI) caused by xenobiotics (drugs, herbals and dietary supplements)
is an uncommon cause of liver disease presenting with a wide range of phenotypes and
disease severity, acute ...
Mechanistic Insight from Preclinical Models of Parkinson’s Disease Could Help Redirect Clinical Trial Efforts in GDNF Therapy
(Int. J. Mol. Sci, 2021)
Parkinson’s disease (PD) is characterized by four pathognomonic hallmarks: (1) motor
and non-motor deficits; (2) neuroinflammation and oxidative stress; (3) pathological aggregates of
the α-synuclein (α-syn) protein; (4) ...
What trauma patients need: the European dilemma
(European Journal of Trauma and Emergency Surgery, 2022)
There is a need for implementation and maturation of an inclusive trauma system in every country in Europe, with patient centered care by dedicated surgeons. This process should be initiated by physicians and medical ...
Physical and Chemical Characterisation of the Pigments of a 17th-Century Mural Painting in the Spanish Caribbean
(MDPI, 2021)
The arrival of Spaniards in the Caribbean islands introduced to the region the practice of
applying pigments onto buildings. The pigments that remain on these buildings may provide data
on their historical evolution and ...
FMNL2 regulates gliovascular interactions and is associated with vascular risk factors and cerebrovascular pathology in Alzheimer’s disease
(Acta Neuropathologica (2022) 144:59–79, 2022-05-24)
Alzheimer’s disease (AD) has been associated with cardiovascular and cerebrovascular risk factors (CVRFs) during middle
age and later and is frequently accompanied by cerebrovascular pathology at death. An interaction ...
Comparison of in‑hospital and out‑of‑hospital cardiac arrest of trauma patients in Qatar
(International Journal of Emergency Medicine, 2022)
Cardiac arrests in admitted hospital patients with trauma have not been described in the literature. We
defined “in-hospital cardiac arrest of a trauma” (IHCAT) patient as “cessation of circulatory activity in a trauma ...
Progranulin mutations in clinical and neuropathological Alzheimer’s disease
(Alzheimers Dement., 2022-12-10)
Progranulin (GRN) mutations occur in frontotemporal lobar degeneration
(FTLD) and in Alzheimer’s disease (AD), often with TDP-43 pathology.
We determined the frequency of rs5848 and rare, pathogenic GRN mutations
in two ...