Artículos: Envíos recientes
Mostrando ítems 201-220 de 280
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The neurovascular unit dysfunction in Alzheimer’s disease
(International Journal o f Molecular Sciences, 2021-02-16)Alzheimer’s disease (AD) is the most common neurodegenerative disease worldwide. Histopathologically, AD presents with two hallmarks: neurofibrillary tangles (NFTs), and aggregates of amyloid peptide (A ) both in the ... -
Molecular Processing of Tau Protein in Progressive Supranuclear Palsy: Neuronal and Glial Degeneration
(IOS Press BV, 2021)Alzheimer's disease (AD) and progressive supranuclear palsy (PSP) are examples of neurodegenerative diseases, characterized by abnormal tau inclusions, that are called tauopathies. AD is characterized by highly insoluble ... -
Human Dental Pulp Stem Cells Display a Potential for Modeling Alzheimer Disease-Related Tau Modifications
(Frontiers Media S. A., 2021)We present here the first description of tau in human dental pulp stem cells (DPSCs) evidenced by RT-PCR data on expression of the gene MAPT and by immunocytochemical detection of epitopes by 12 anti-tau antibodies. The ... -
Dementia Research in the Caribbean Hispanic Islands: Present Findings and Future Trends
(Front. Public Health, 2021-01-18)During the last decade, the Caribbean Hispanic islands experienced accelerated demographic aging, representing the fastest aging region within Latin America. Age-related non-communicable diseases, including dementia, are ... -
Long-term stability of two-phase class II: treatment with the carriere motion appliance
(Journal of Clinical Orthodontics, 2019-08) -
The colour of architecture: physical-chemical analysis of polychromy on stone in a 16th century gothic Portal at the Cathedral of Santo Domingo
(IOP Publishing, 2020)Colour always played a role in the human evolutionary process and has been used as a way of expression. But the time, the lack of maintenance and abandonment, the lack of studies related to the presence of polychromy in ... -
Applications of non-destructive techniques in the study of a Caribbean historic timber house.
(IOP Publishing, 2020)The aims of this research is to analysis a Caribbean historic timber house using nondestructive techniques (NDT). The high cultural and historic value that have the timber buildings in the Caribbean and the necessity to ... -
Seroprevalence of specific antibodies against SARS-CoV-2 from hotspot communities in the Dominican Republic.
(The American Society of Tropical Medicine and Hygiene, 2020)Seroprevalence surveys are of utmost importance to assess the proportion of a population that has developed antibodies against a newly introduced virus and could therefore potentially exhibit immunologic protection against ... -
The effect of massive transfusion protocol implementation on the survival of trauma patients: a systematic review and meta-analysis
(Blood Transfus, 2020-03-15)Massive transfusion protocol (MTP) has been widely adopted for the care of bleeding trauma patients but its actual effectiveness is unclear. An earlier meta-analysis on the implementation of MTP for injured patients from ... -
Clinical validation demonstrates concordance of qSOFA and POC lactate Bayesian model: Results from the ACDC Phase-2 program
(American Journal of Emergency Medicine, 2020-10-01)La sepsis es un problema médico común y letal. El objetivo de este estudio fue validar un Modelo Bayesiano que integra qSOFA y Lactato prehospitalario, con un análisis comparativo a partir de datos clínicos reales de ... -
Neighbourhood environment and dementia in older people from high-, middle- and low-income countries: results from two population-based cohort
(BMC Public Health, 2020)A growing number of studies have explored how features of the neighbourhood environment can be related to cognitive health in later life. Yet few have focused on low- and middle-income countries and compared the results ... -
Prehospital administration of tranexamic acid in trauma patients: A 1:1 matched comparative study from a level 1 trauma center
(American Journal of Emergency Medicine, 2019)The purpose of this study was to test the efficacy of prehospital administration of tranexamic acid (TXA) to injured patients on mortality, thromboembolic events and need for blood transfusion in a level 1 trauma center. ... -
Natural disasters
(2019)Natural disasters can cause a rupture of the daily routine with an essential impact on the local resources and the standard functionality of the population. It is critical that as health care personnel, we are familiar ... -
Coagulopathy in the surgical patient: trauma-induced and drug-induced coagulopathies
(Wolters Kluwer Health, 2019)Purpose of review coagulopathy is the derangement of hemostasis that in surgical patients may result in excessive bleeding, clotting or no measurable effect. The purpose of this review is to provide an overview of the ... -
Racial and gender disparities in violent trauma: results from the NEMSIS database
(American Journal of Emergency Medicine, 2018-04)Barriers to EMS care can result in suboptimal outcomes and preventable morbidity and mortality. Large EMS databases such as the National Emergency Medical Services Information System (NEMSIS) dataset provide valuable ... -
Latin America intensive care unit disaster preparedness: results from a web‑based attitudes and perceptions survey
(International Journal of Critical Illness and Injury Science | Published by Wolters Kluwer - Medknow, 2019-11-11)Disasters burden on hospital emergency intensive care units (ICUs). This burden is increased in Latin America (LATAM) where hospital resources, intrahospital disaster simulations, and perceived level of preparedness vary ... -
The 10/66 Dementia Research Group's fully operationalised DSM-IV dementia computerized diagnostic algorithm, compared with the 10/66 dementia algorithm and a clinician diagnosis: a population validation study
(BMC Public Health, 2007-07-20)Latin America, China and India are experiencing unprecedentedly rapid demographic ageing with an increasing number of people with dementia. The 10/66 Dementia Research Group's title refers to the 66% of people with dementia ... -
Prediction of dementia risk in low-income and middleincome countries (the 10/66 Study): an independent external validation of existing models
(Elsevier Ltd, 2020-04)To date, dementia prediction models have been exclusively developed and tested in high-income countries (HICs). However, most people with dementia live in low-income and middle-income countries (LMICs), where dementia ... -
Prevalence, distribution, and impact of mild cognitive impairment in Latin America, China, and India: a 10/66 population-based study.
(PLoS Medicine | www.plosmedicine.org, 2012-02)Rapid demographic ageing is a growing public health issue in many low- and middle-income countries (LAMICs). Mild cognitive impairment (MCI) is a construct frequently used to define groups of people who may be at risk ... -
Alcoholrelated liver disease clinical practice guidelines by the Latin American Association for the Study of the Liver ALEH.
(Elsevier España, 2019)Alcohol-related liver disease (ALD) is a major cause of advanced chronic liver disease in Latin-America, although data on prevalence is limited. Public health policies aimed at reducing the alarming prevalence of alcohol ...